Inter Milan defeated Bologna 3-1 to move atop Serie A with 19 points. Tommaso Pobega gave Bologna an early lead in the 10th minute, but Marcus Thuram equalized with a header. Manager Simone Inzaghi's substitutions turned the match as Carlos Augusto scored midway through the second half and set up Ange-Yoan Bonny for the clincher. Inter played without injured captain Lautaro Martinez, sidelined for a month.
Roma beat Genoa 2-0 to jump into second place, two points behind Inter. Santiago Castro and Emanuele Lulli each scored their first goals for the club, with Castro's flicked finish breaking the deadlock in the 50th minute. Genoa coach Daniele De Rossi, a former Roma figure, received applause from the home crowd but could not prevent the loss.
Napoli suffered a shocking 1-0 defeat to Venezia, their fifth loss in nine matches. New Venezia manager Davide Nicola secured an immediate impact on debut as Akor Adams scored early in the second half. Kevin De Bruyne's penalty attempt was saved by Filip Stankovic, leaving Napoli ninth, nine points off the pace.
