RB Leipzig face Manchester City at Red Bull Arena on Wednesday, 4 November 2026 at 20:00 GMT in the Champions League league phase. City sit 10th with six points from three matches following back-to-back Premier League defeats to Aston Villa and Brighton. Leipzig are 29th on three points, managed by former City defender Martín Demichelis, who made 15 Champions League appearances for the club.
Leipzig will be without Assan Ouédraogo and Marc Guiu through injury, while Maxime Estève and Christopher Nkunku remain doubtful. Antonio Nusa, who has five goals this season, is expected to feature on the left wing alongside midfielder Christoph Baumgartner. City's Antoine Semenyo is sidelined until mid-December, but Phil Foden and Rayan Cherki are available after the hat-trick scorer's recent performance against AEK Athens. Erling Haaland, with 12 goals in eight career matches against Leipzig, leads City's attacking threat.
City have struggled with early defensive lapses, conceding within 15 minutes three times this season. Leipzig's recent form shows three consecutive wins in the Bundesliga, though they have lost their last five European matches against English opposition.
