Italian clubs suffered a disappointing European week, losing all four Champions League matches for the first time in history. The weekend offers Serie A teams a chance to recover quickly. Several key storylines will shape Matchday 7 across the league.

Inter travel to Bologna at 18:00 without captain Lautaro Martinez, who will miss nearly a month through injury. Roma host Genoa in the evening but face their own personnel issues with Malen suspended. Roma appear better positioned to cope with their absence given home advantage and the quality of opposition. Venezia begin their manager search under Davide Nicola's debut, hosting Napoli at 15:00 after a disastrous start has left them pointless and four adrift of safety.

Como need points at Fiorentina to maintain contact with the league's top teams after recording two defeats and a draw in their last three matches. Fiorentina themselves sit near the bottom and require a win to stabilize their season after mixed results under new management.